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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYTL1
All Species:
24.24
Human Site:
S421
Identified Species:
59.26
UniProt:
Q8IYJ3
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IYJ3
NP_116261.1
562
61857
S421
E
G
A
G
L
P
P
S
G
E
L
H
F
W
V
Chimpanzee
Pan troglodytes
XP_513243
562
61857
S421
E
G
A
G
L
P
P
S
G
E
L
H
F
W
V
Rhesus Macaque
Macaca mulatta
XP_001110913
562
61901
S421
E
G
A
G
L
P
P
S
G
E
L
H
F
W
V
Dog
Lupus familis
XP_544472
575
63091
S434
E
G
P
G
L
P
P
S
G
E
L
H
F
W
V
Cat
Felis silvestris
Mouse
Mus musculus
Q99N80
567
62343
S426
E
G
G
G
Q
P
Q
S
G
E
L
H
F
W
V
Rat
Rattus norvegicus
Q8VHQ7
672
75882
G526
K
K
S
K
G
G
E
G
G
E
L
Q
V
W
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P47191
424
47487
N301
V
V
I
L
E
A
K
N
L
K
K
M
D
V
G
Frog
Xenopus laevis
NP_001086662
523
58782
T383
E
G
L
G
L
P
P
T
G
E
L
H
V
W
I
Zebra Danio
Brachydanio rerio
NP_001122005
539
60929
T399
E
G
R
G
N
P
A
T
G
E
L
H
I
W
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P21521
474
53246
N351
V
V
I
L
E
A
K
N
L
K
K
M
D
V
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
96
82.9
N.A.
81.1
32.5
N.A.
N.A.
22.2
45.7
42.8
N.A.
25.2
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
97.3
87.4
N.A.
87.3
48.2
N.A.
N.A.
40
61.3
57.8
N.A.
42.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
80
26.6
N.A.
N.A.
0
73.3
60
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
80
46.6
N.A.
N.A.
13.3
86.6
73.3
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
30
0
0
20
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% D
% Glu:
70
0
0
0
20
0
10
0
0
80
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% F
% Gly:
0
70
10
70
10
10
0
10
80
0
0
0
0
0
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
70
0
0
0
% H
% Ile:
0
0
20
0
0
0
0
0
0
0
0
0
10
0
20
% I
% Lys:
10
10
0
10
0
0
20
0
0
20
20
0
0
0
0
% K
% Leu:
0
0
10
20
50
0
0
0
20
0
80
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
20
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
70
50
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
10
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
50
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% T
% Val:
20
20
0
0
0
0
0
0
0
0
0
0
20
20
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
80
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _